NOTE: This report is compiled on an ongoing basis by MLSsoccer.com editors based on club game notes, news reports, and original reporting. The league does not have an official player availability report.
- OUT: Ozzie Alonso (leg)
Austin FC
- OUT: Zan Kolmanic (right ACL)
- QUESTIONABLE: Gyasi Zardes (left calf tightness)
- OUT: Hamady Diop (athletic pubalgia)
- OUT: Vinicius Mello (right lower leg)
- QUESTIONABLE: Brecht Dejaegere (right thigh)
- OUT: Chris Mueller (right upper leg)
- OUT: Javier Casas (right lower leg)
- OUT: Victor Bezerra (right lower leg)
- OUT: Federico Navarro (left lower leg)
- OUT: Kacper Przybylko (left lower leg)
- QUESTIONABLE: Jonathan Dean (left upper leg)
- QUESTIONABLE: Carlos Teran (left upper leg)
- OUT: Stiven Jimenez (lower leg fracture)
Colorado Rapids
- OUT: William Yarbrough (knee surgery)
- OUT: Alex Gersbach (adductor tendon surgery)
- OUT: Jack Price (Achilles)
- OUT: Max (removed from team activities)
- OUT: Aboubacar Keita (lower body)
- OUT: Will Sands (knee)
FC Dallas
- OUT: Tarik Scott (season-ending injury)
- OUT: Alan Velasco (right calf)
- OUT: Bernard Kamungo (right shoulder)
- OUT: Geovane Jesus (right knee)
- QUESTIONABLE: Antonio Carrera (left ankle)
- QUESTIONABLE: Ema Twumasi (right shoulder)
D.C. United
- OUT: Martin Rodriguez (knee)
- OUT: Mohanad Jeahze (ankle)
- OUT: Tyler Miller (shoulder)
- OUT: Derrick Williams (calf)
- QUESTIONABLE: Steve Birnbaum (hip)
- QUESTIONABLE: Andy Najar (thigh)
- QUESTIONABLE: Ted Ku-DiPietro (thigh)
Houston Dynamo FC
- OUT: Ifunanyachi Achara (knee)
- OUT: Tate Schmitt (knee)
- OUT: None
- OUT: Javier "Chicharito" Hernandez (torn ACL, right knee)
- OUT: Gaston Brugman (torn meniscus, left knee)
- OUT: Calegari (knee)
- OUT: Martin Caceres (avulsion fracture, left knee)
- QUESTIONABLE: Jalen Neal (abdomen)
Inter Miami CF
- OUT: Gregore (Lisfranc)
- OUT: Ian Fray (ACL)
- OUT: Franco Negri (ACL)
- OUT: Corentin Jean (ACL)
Minnesota United FC
- OUT: Ryen Jiba (knee)
- OUT: Robin Lod (knee)
- OUT: Kervin Arriaga (knee)
- OUT: Aaron Herrera (ankle)
- OUT: Robert Thorkelsson (adductor)
- QUESTIONABLE: Romell Quioto (hamstring)
Nashville SC
- OUT: Nick DePuy (lower body)
- QUESTIONABLE: Walker Zimmerman (lower body)
- QUESTIONABLE: Sam Surridge (lower body)
- QUESTIONABLE: Randall Leal (lower body)
- OUT: Dylan Borrero (left knee season ending)
- OUT: Brandon Bye (right ACL season ending)
- OUT: Henry Kessler (right hamstring)
- OUT: Maciel (left Achilles)
- OUT: Tomas Vaclik (pending arrival)
- QUESTIONABLE: Gustavo Bou (right leg)
New York City FC
- OUT: None
New York Red Bulls
- OUT: Serge Ngoma (hamstring)
- OUT: Lewis Morgan (hip)
- QUESTIONABLE: Dante Vanzeir (thigh)
- QUESTIONABLE: Cory Burke (groin)
- QUESTIONABLE: Steven Sserwadda (knee)
- QUESTIONABLE: Dylan Nealis (hip)
Orlando City SC
- OUT: Antonio Carlos (right lower leg)
- OUT: Favian Loyola (left arm)
- QUESTIONABLE: Gaston Gonzalez (left thigh)
Philadelphia Union
- OUT: Leon Flach (core)
Portland Timbers
- OUT: David Ayala (left knee)
- OUT: Jaroslaw Niezgoda (right knee)
- OUT: Eryk Williamson (right knee)
- OUT: Diego Chara (abdomen)
- OUT: Aljaz Ivacic (lumbar)
Real Salt Lake
- OUT: Erik Holt (shoulder)
- OUT: Pablo Ruiz (knee)
- OUT: Nathan (ACL)
- OUT: Benji Kikanovic (lower body)
- OUT: Jack Skahan (lower body)
- QUESTIONABLE: Judson (lower body)
- QUESTIONABLE: Daniel Munie (lower body)
Seattle Sounders FC
- OUT: Kelyn Rowe (right quad strain)
- QUESTIONABLE: Cristian Roldan (concussion protocol)
- QUESTIONABLE: Cody Baker (concussion protocol)
Sporting Kansas City
- OUT: Kortne Ford (Achilles surgery)
- OUT: Kayden Pierre (hamstring)
- QUESTIONABLE: Stephen Afrifa (hamstring)
- QUESTIONABLE: Gadi Kinda (ankle)
- QUESTIONABLE: Graham Zusi (hamstring)
- QUESTIONABLE: Johnny Russell (ankle)
- QUESTIONABLE: Rasmus Alm (groin)
Toronto FC
- OUT: Adama Diomande (lower body)
- OUT: Sean Johnson (hand surgery)
- OUT: Cristian Gutierrez (lower body)
- OUT: Cassius Mailula (lower body)
- OUT: Greg Ranjitsingh (knee surgery)
- OUT: Prince Owusu (lower body)
Vancouver Whitecaps FC
- OUT: Luis Martins (left calf strain)
- OUT: Thomas Hasal (patellar tendinopathy)
- QUESTIONABLE: Sam Adekugbe (right patella tendinitis)
